Abstract
WHEN plasma containing platelets clots at 37° C., the adenosine triphosphate in the platelets rapidly breaks down; little or none of it appears in the serum1. It has now been found that during clotting an increased amount of phosphate becomes bound to protein. The phosphate seems to come partly from platelet adenosine triphosphate and partly from phospholipid. One of the experiments which demonstrated this was as follows.
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References
Born, G. V. R., J. Physiol., 133 61, P (1956).
Berenblum, J., and Chain, E., Biochem. J., 32, 295 (1938).
Folch, J., Lees, M., and Sloane-Stanley, G. H., Fed. Proc., 13, 209 (1954).
Fantl, P., and Ward, H. A., Biochem. J., 64, 747 (1956).
Hardisty, R. M., and Pinniger, J. L., Brit. J. Haematol., 2, 139 (1956).
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BORN, G. Evidence for the Formation of a Labile Phospholipoprotein during the Clotting of Platelet-rich Plasma. Nature 180, 546–547 (1957). https://doi.org/10.1038/180546a0
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DOI: https://doi.org/10.1038/180546a0
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