Abstract
IN the course of a study on the protection of mice against a lethal dose of X-rays, it was found in this laboratory that the administration of homologous or heterologous (rat) bone marrow after the irradiation may result in a significant reduction of mortality. In the animals surviving after heterologous therapy the circulating erythrocytes were agglutinated by anti-rat serum ; furthermore, the granulocytes showed an alkaline phosphatase reaction which is specific for rat white cells. These results proved that a transplantation of rat hæmatopoietic tissue had been achieved1.
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References
Vos, O., Davids, J. A. G., Weyzen, W. W. H., and van Bekkum, D. W., Acta Physiol. Pharmacol. Neerl., 4, 482 (1956).
Makinodan, T., Proc. Soc. Exp. Biol. Med., 92, 174 (1956).
Scheidegger, J. J., Int. Arch. Allergy and Appl. Immunol., 7, 103 (1955).
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WEYZEN, W., Vos, O. Production of Rat Serum Proteins in Irradiated Mice. Nature 180, 288–289 (1957). https://doi.org/10.1038/180288b0
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DOI: https://doi.org/10.1038/180288b0
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