Abstract
REMARKABLE similarities have been found between the biological properties of animal viruses containing ribonucleic acid and those of viruses containing deoxyribonucleic acid (such as bacteriophages). The question has thus been raised whether the mechanism of duplication of the two types of virus may involve common steps1. One possibility is that viruses containing ribonucleic acid have an intracellular deoxyribonucleic acid phase. With this point in mind, extensive cytochemical investigations of the changes occurring in the nucleic acids of cells infected by poliomyelitis virus have been carried out.
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References
Dulbecco, R., Ciba Fundation Symposium on the Nature of Viruses, 147 (1956).
Dulbecco, R., and Vogt, M., Ann. New York Acad. Sci., 61, 790 (1955).
Bertelanffy, L., et al., Histochem. Cytochem., 4, 481 (1956). Armstrong, T. A., Exp. Cell. Res., 11, 640 (1956). Smiles, J., and Taylor, A. E. R., Nature, 179, 306 (1957).
Reissig, M., Howes, D. W., and Melnick, J. L., J. Exp. Med., 104, 289 (1956).
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TENENBAUM, E. Changes in Cellular Nucleic Acids during Infection with Poliomyelitis Virus as studied by Fluorescence Microscopy. Nature 180, 1044 (1957). https://doi.org/10.1038/1801044a0
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DOI: https://doi.org/10.1038/1801044a0
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