Blood Group Antigens Mia and Vw and their Relation to the MNSs System


THE blood group antigen Mia was discovered by Levine, Stock, Kuhmichel and Bronikovsky1 in 1951. Anti-Mia, the antibody necessary for the identification of the antigen, was made by a mother in response to immunization by her Mi(a +) fœtus which, as a result, had severe hæmolytic disease. The antigen was shown to be inherited as a dominant character. The antigen was evidently rare, for no example was found in testing 425 random people.

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  1. 1

    Levine, P., Stock, A. H., Kuhmichel, A. B., and Bronikovsky, N., Proc. Soc. Exp. Biol., N.Y., 77, 402 (1951).

  2. 2

    v. d. Hart, Mia, Bosman, Hélène, and van Loghem, J. J., Vox Sanguinis, 4, 108 (1954).

  3. 3

    Levine, P., Robinson, E. A., Layrisse, M., Arends, T., and Sisco, R. D., Nature, 177, 40 (1956).

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WALLACE, J., MILNE, G., MOHN, J. et al. Blood Group Antigens Mia and Vw and their Relation to the MNSs System. Nature 179, 478 (1957) doi:10.1038/179478a0

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