Abstract
THE recent communications of Stern1, and Hough, Barnard and Bassir2, have dealt with equations for the mathematical interpretation of experimental urinary excretion data. Approximately exponential excretion appears to be typical of the process for a number of substances taken into the body; and several experimentalists have employed this concept3–5. The rate constants which may be determined lend themselves to convenient tabulation or discussion in terms of scalar units6–8.
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References
Stern, B. E., Nature, 175, 258 and 776 (1955).
Hough, J., Barnard, H., and Bassir, O., Nature, 175, 776 (1955).
Lapp, C., Produits Pharmaceutiques, 9, 566 (1954).
Haigh, C. P., and Reiss, M., Brit. J. Radiol., 23, 534 (1950).
Teorell, T., Arch. intern. pharmacodynamie, 57, 205 and 226 (1937).
Swintosky, J. V., J. Amer. Pharm. Assoc., Sc. Ed., 45, 395 (1956).
Swintosky, J. V., Robinson, M. J., and Foltz, E. L. (to be published).
Swintosky, J. V., et al. (to be published).
Friedman, M., Bine, Jr., R., Byers, S. O., and Bland, C., Circulation, 2, 749 (1950).
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SWINTOSKY, J. Excretion Equations and Interpretation for Digitoxin. Nature 179, 98–99 (1957). https://doi.org/10.1038/179098b0
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DOI: https://doi.org/10.1038/179098b0
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