Adrenaline and Noradrenaline in Adrenal Autografts


BOTH cortical and medullary cells survive in adrenal grafts months after transplantation into the anterior chamber of the eye1. It is, however, not known whether the two medullary hormones, adrenaline and noradrenaline, are present in the grafts. Moreover, all previous work has been without regard to the fact that there are two different types of cells in the adrenal medulla2. A substantial body of evidence is now available indicating that one of these cell types contains and secretes adrenaline, and the other noradrenaline3,4. It seemed therefore to be of interest to investigate adrenal grafts by chemical and histochemical methods which differentiate between adrenaline and noradrenaline.

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    Hillarp, N. Å., and Hökfelt, B., Endocrinol., 55, 255 (1954); J. Histochem. Cytochem., 3, 1 (1955).

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    Eränkö, O., Ann. Med. Exp. Biol. Fenniæ, 32, 392 (1954); 3, 3, 278 (1955); Nature, 175, 88 (1955); Endocrinol., 57, 363 (1955).

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