Abstract
DESPITE assiduous search by many workers, the factor conferring the property of high virulence on strains of P. pestis has remained undetected. Virulent and protective avirulent strains have been studied comparatively by the methods of immunology, immunochemistry and biochemistry without yielding convincing evidence of a difference in their properties sufficient to account for their difference in virulence. This communication reports results showing that an important antigenic difference between virulent and protective avirulent strains does in fact exist.
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References
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BURROWS, T. An Antigen determining Virulence in Pasteurella pestis . Nature 177, 426–427 (1956). https://doi.org/10.1038/177426b0
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DOI: https://doi.org/10.1038/177426b0
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