Abstract
A SMALL number of hæmophilic patients at first benefit by blood or plasma transfusions but later develop in their blood an anticoagulant which renders further transfusions temporarily ineffective. It is believed that the anticoagulant is an antibody due to the transfused antigen1, but positive precipitin tests have been obtained infrequently.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Craddock, C. S., and Lawrence, J. S., Blood, 2, 505 (1947).
Aggeler, P. M., White, S. G., Glendening, M. B., Page, E. P., Leake, T. B., and Bates, G., Proc. Soc. Exp. Biol. Med., 79, 162 (1952).
Biggs, R., Douglas, A. S., MacFarlane, R. G., Dacie, J. V., Pitney, W. R., Merskey, C., and O'Brien, J. R., Brit. Med. J., ii, 1378 (1952).
Bell, W. N., and Alton, H. G., Nature, 174, 880 (1954).
Fantl, P., Aust. J. Exp. Biol. Med. Sci., 32, 853 (1954).
Frommeyer, W. B., Epstein, R. D., and Taylor, F. H. L., Blood, 5, 401 (1950).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
FANTL, P., SAWERS, R. Anticoagulant Specificity and Physiologically Inactive Beta-Prothromboplastin. Nature 177, 1233–1234 (1956). https://doi.org/10.1038/1771233a0
Issue Date:
DOI: https://doi.org/10.1038/1771233a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
