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Production of ‘O Inagglutinability’ in Erythrocytes coated with Typhoid Vi and O Antigens

Nature volume 176, pages 1266–1267 (1955)Cite this article

Abstract

STRAINS of Salmonella typhosa resistant to agglutination by O antibody, although containing the characteristic O antigen, were observed by Felix and Pitt to be considerably more virulent for mice than strains which were readily agglutinated by O antibody. This ‘O inagglutinability’ of virulent typhoid cultures was eventually shown by these workers to be associated with the presence of an additional component, the Vi antigen, which had a pronounced effect on the behaviour of the O antigen1.

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References

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Authors and Affiliations

  1. Army Medical Service Graduate School, Washington, D.C.

    MAURICE LANDY

  2. Istituto Sieroterapico Milanese Serafino Belfanti, Milan

    RUGGERO CEPPELLINI

Authors
  1. MAURICE LANDY
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  2. RUGGERO CEPPELLINI
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LANDY, M., CEPPELLINI, R. Production of ‘O Inagglutinability’ in Erythrocytes coated with Typhoid Vi and O Antigens. Nature 176, 1266–1267 (1955). https://doi.org/10.1038/1761266a0

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