Abstract
MARKED changes may be produced by virus infection in a host cell when the amount of virus material is very small compared with the amount of host cell and when some of the host's synthetic activities are altered by the presence of the virus. Many authors refer to this control of the cell by the infecting particle; but experimental evidence is very scanty. In infection by coliphage T 2, Cohen1 has shown that infected cells use an alternative metabolic pathway to a greater extent than do normal cells. No definite information is available in mammalian virus infections as to the presence of such metabolic alterations, nor the means by which such changes could be produced.
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References
Cohen, S. S., Nature, 168, 746 (1951).
Nossal, G. J. V., and de Burgh, P. M., J. Gen. Microbiol., 10, 345 (1954).
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DE BURGH, P., MILLER, J. Cellular Control in Virus Infection. Nature 175, 550 (1955). https://doi.org/10.1038/175550a0
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DOI: https://doi.org/10.1038/175550a0
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