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Crystalline-like Patterns in the Nuclei of Cells infected with an Animal Virus

Abstract

A GROUP of viruses causing very peculiar changes of the infected cells in tissue cultures was recently isolated in our laboratory1. The strains were obtained from cases of either mesenteric lymphadenitis or pharyngitis with cervical lymphadenitis. An apparently identical microscopical picture1 was caused by agents described by Neva and Enders2 and Hilleman and Werner3. So far, all strains exhibiting this pattern of cytopathic activity which have been tested in our laboratory have had complement-fixing antigens in common, although by neutralization tests they could be differentiated into three types1.

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References

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KJELLÉN, L., LAGERMALM, G., SVEDMYR, A. et al. Crystalline-like Patterns in the Nuclei of Cells infected with an Animal Virus. Nature 175, 505–506 (1955). https://doi.org/10.1038/175505a0

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