Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Chemical Properties of a Plasma Factor accelerating Hæmoglobin Recovery in Bled Rabbits

Nature volume 175, pages 167–168 (1955)Cite this article

Abstract

IT has been shown that plasma of repeatedly bled rabbits—referred to here as ‘anæmic plasma’—contains a factor (or factors) which accelerates the recovery of hæmoglobin concentration after a standard hæmorrhage1 and produces a greater reticulocyte response in receptor animals2; when injected repeatedly into normal rabbits, ‘anæmic plasma’ significantly increases the hsemoglobin concentration, red cell and reticulocyte counts3. After boiling ‘anæmic plasma’ at pH 5.5, the supernatant, separated from the precipitated proteins, is inactive1.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Hodgson, G., and Tohá, J., Blood, 9, 299 (1954).

    CAS  PubMed  Google Scholar 

  2. Günther, B., Hodgson, G., Tohá, J., and Quappe, O., Acta Physiol. Latinoamer., 1, 271 (1951).

    Google Scholar 

  3. Tohá, J., Hodgson, G., and Weasson, E., Proc. Fourth Int. Cong. Int. Soc. Hematology, 58 (Grune and Stratton, New York, 1954).

  4. Contopoulus, A. N., Van Dyke, D. C., Simpson, M. E., Garcia, J. F., Huff, R. L., Williams, B. S., and Evans, H. M., Blood, 8, 131 (1953).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology, University of Concepción, Cas : 44, Concepción, Chile

    J. TOHÁ, I. ESKUCHE, F. ABARCA, F. SALVATORE & G. HODGSON

Authors
  1. J. TOHÁ
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. I. ESKUCHE
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. F. ABARCA
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. F. SALVATORE
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. G. HODGSON
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

TOHÁ, J., ESKUCHE, I., ABARCA, F. et al. Chemical Properties of a Plasma Factor accelerating Hæmoglobin Recovery in Bled Rabbits. Nature 175, 167–168 (1955). https://doi.org/10.1038/175167b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/175167b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing