Abstract
FORSSBERG1 reported that cysteine and glutathione did not protect catalase against inactivation by X-rays, but on the contrary increased the radiation effect on the enzyme. Most organic substances act as protectors when added as a second solute to the solution of the primary solute. Since cysteine and glutathione have been used in protection experiments in vivo 2,3 and in vitro 4,5 it was decided to re-investigate the inactivation of catalase by irradiation, in view of the apparently exceptional nature of the effect of these substances.
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References
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DALE, W., RUSSELL, C. Action of Ionizing Radiations on Catalase in Presence of Cysteine, Cystine and Glutathione. Nature 175, 33–34 (1955). https://doi.org/10.1038/175033b0
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DOI: https://doi.org/10.1038/175033b0
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