Abstract
IT is now widely accepted that, provided the sympathetic innervation is intact, adrenaline is discharged continuously from the suprarenal medulla, even under basal conditions. Several authors1 found a basal discharge of 0.03–0.06 µgm./kgm./min. from the two suprarenals of cats and dogs. According to our results2, the adrenaline arteriovenous difference in man is about 0.5 µgm./l. of blood, which corresponds, as a first approximation, to a rate of utilization of about 0.03 µgm./kgm./min.—a value in good agreement with the established rate of adrenaline discharge.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Kaindl, F., and Euler, U. S. von, Amer. J. Physiol., 166, 284 (1951). Dunér, H., Acta Physiol. Scand., 28, Supp. 102 (1953). Houssay, A., and Rapela, C. F., Arch. Exp. Path. Pharmak., 219, 156 (1953). Wada, M., and Kanowoka, K., Tohoku J. Exp. Med., 27, 1 (1935).
Weil-Malherbe, H., and Bone, A. D., Biochem. J., 58, 132 (1954).
Weil-Malherbe, H., and Bone, A. D., Lancet, 264, 974 (1953).
Holzbauer, M., and Vogt, M., Brit. J. Pharmacol., 9, 249 (1954).
Weil-Malherbe, H., and Bone, A. D., J. Endocrinol. (in the press).
Weil-Malherbe, H., and Bone, A. D., Biochem. J., 51, 311 (1952).
Lund, A., Acta Pharmacol., 6, 137 (1950).
Code, C. F., Physiol. Rev., 32, 47 (1952).
Rand, M. and Reid, G., Nature, 168, 385 (1951).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WEIL-MALHERBE, H., BONE, A. Blood Platelets as Carriers of Adrenaline and Noradrenaline. Nature 174, 557–558 (1954). https://doi.org/10.1038/174557b0
Issue Date:
DOI: https://doi.org/10.1038/174557b0
This article is cited by
-
Central and peripheral nervous systems: master controllers in cancer metastasis
Cancer and Metastasis Reviews (2013)
-
Der Schock und seine Behandlung mit ?-Aminocaprons�ure (EACS)
Acta Neurovegetativa (1965)
-
The mechanism of action of insulin
Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie (1955)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.