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Blood Platelets as Carriers of Adrenaline and Noradrenaline

Abstract

IT is now widely accepted that, provided the sympathetic innervation is intact, adrenaline is discharged continuously from the suprarenal medulla, even under basal conditions. Several authors1 found a basal discharge of 0.03–0.06 µgm./kgm./min. from the two suprarenals of cats and dogs. According to our results2, the adrenaline arteriovenous difference in man is about 0.5 µgm./l. of blood, which corresponds, as a first approximation, to a rate of utilization of about 0.03 µgm./kgm./min.—a value in good agreement with the established rate of adrenaline discharge.

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References

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WEIL-MALHERBE, H., BONE, A. Blood Platelets as Carriers of Adrenaline and Noradrenaline. Nature 174, 557–558 (1954). https://doi.org/10.1038/174557b0

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