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Independence of Delayed Fertilization and Spontaneous Triploidy in Mouse Embryos

Nature volume 174, pages 356–357 (1954)Cite this article

Abstract

IN the early mouse embryo, spontaneous1 or experimentally induced2 triploidy is thought to arise by fertilization of an unreduced diploid egg by a haploid normal sperm. The possibility has not been wholly excluded that the extra set of chromosomes is derived instead from the male3—for example, double fertilization or diploid sperm—or after delayed fertilization4. In the rat and rabbit, Austin and Braden5 showed that experimentally delayed fertilization causes polyspermy; in the rat, chromosome counts at the first cleavage division showed that some dispermic eggs were triploid. It was suggested6 that some of the spontaneously triploid mouse embryos might have arisen in this way, and not by doubling of the maternal chromosomes.

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References

  1. Beatty, R. A., and Fischberg, M., J. Genetics, 50 345 (1951).

    Article  CAS  Google Scholar 

  2. Fischberg, M., and Beatty, R. A., J. Genetics, 50, 455 (1951).

    Article  Google Scholar 

  3. Fischberg, M., and Beatty, R. A., Evolution, 6, 316 (1952).

    Article  Google Scholar 

  4. Beatty, R. A., Anim. Breed. Abstr., 19, 283 (1951).

    Google Scholar 

  5. Austin, C. R., and Braden, A. W. H., Aust. J. Biol. Sci., 6, 674 (1953).

    Article  CAS  Google Scholar 

  6. Austin, C. R., and Braden, A. W. H., Nature, 172, 82 (1953).

    Article  CAS  Google Scholar 

  7. Runner, M. N., and Gates, A. H., Nature [174, 222 (1954)].

    Article  ADS  CAS  Google Scholar 

  8. Runner, M. N., and Palm, J., J. Exp. Zool., 124, 303 (1953).

    Article  Google Scholar 

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Authors and Affiliations

  1. Institute of Animal Genetics, King's Buildings, West Mains Road, Edinburgh, 9

    A. H. GATES & R. A. BEATTY

Authors
  1. A. H. GATES
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  2. R. A. BEATTY
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GATES, A., BEATTY, R. Independence of Delayed Fertilization and Spontaneous Triploidy in Mouse Embryos. Nature 174, 356–357 (1954). https://doi.org/10.1038/174356a0

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  • DOI: https://doi.org/10.1038/174356a0

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