Fine Structure of Exocrine Cells of the Pancreas


A CYTOLOGICAL study has been carried out on exocrine cells of the pancreas of the mouse with the aid of the electron microscope. The tissue was taken from animals aged two to three months and fixed in osmic acid buffered1 to a pH of 7.4. It was then embedded in n-butyl methacrylate and sections about 400–800 A. thick were cut. Similar tissue, also fixed in buffered osmic acid, was embedded in gelatine for sectioning and examination by light microscopy in order to compare the effects of osmium fixation with those obtained by other fixatives employed in previous studies2,3.

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    Palade, G. E., J. Exp. Med., 95, 285 (1952).

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    Lacy, D., J. Roy. Micr. Soc., 73, 179 (1954).

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    Lacy, D., J. Roy. Micr. Soc. (in tho press).

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    Weiss, J., and Lansing, A. I., Proc. Soc. Exp. Biol. Med., 82, 460 (1953).

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    Ludford, R. J., Brit. J. Cancer, 8, 112 (1953).

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CHALLICE, C., LACY, D. Fine Structure of Exocrine Cells of the Pancreas. Nature 174, 1150–1151 (1954) doi:10.1038/1741150a0

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