Abstract
RESEARCHES carried out during the past few years to investigate the precise mechanism of action of nitrogen mustards and related compounds suggest the primary importance of the 
group, which appears in the molecule of nitrogen mustard, when in aqueous solution, through an intramolecular cyclization process: 
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CARDINALI, G. Mutagenic Activity of Ethylenimine Picrate. Nature 173, 825–826 (1954). https://doi.org/10.1038/173825a0
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DOI: https://doi.org/10.1038/173825a0
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