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Reduction of Tetrazolium Salt

Nature volume 173, pages 774–775 (1954)Cite this article

Abstract

SOME two hundred papers dealing with the chemistry of triphenyltetrazolium chloride and its use as a redox-indicator have been reviewed by Ried1 and Smith2. In spite of its wide use in biology, up to the present little is known about its reducing mechanism, the influence of experimental conditions on it, on its redox-potential, etc., and therefore the results obtained with it are empirical in character. Investigations of the salt by means of polarography and spectrophotometry carried out in this laboratory revealed some aspects which should be considered when using it as a chemical indicator of reducing power in biological reactions.

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References

  1. Ried, W., Angew. Chem., 64, 391 (1952).

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  2. Smith, F. E., Science, 113, 751 (1951).

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  3. Hausser, J., Jerchel, D., and Kuhn, R., Chem. Ber., 82, 195 (1949).

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  4. Jámbor, B., Acta. Chim. Acad. Sci. Hung. (in the press).

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Authors and Affiliations

  1. Institute for Plant Physiology, University of Budapest,

    B. JÁMBOR

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  1. B. JÁMBOR
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JÁMBOR, B. Reduction of Tetrazolium Salt. Nature 173, 774–775 (1954). https://doi.org/10.1038/173774b0

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  • DOI: https://doi.org/10.1038/173774b0

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