Abstract
IN attempting to repeat some experiments reported by von Buzagh1, it was noticed that the fibrous precipitate (Fig. 1), formed by adding a 10 per cent sodium chloride solution to a solution of calf Achilles tendon in 1.2 per cent acetic acid, dissolved in 0.9 per cent sodium chloride ; on dialysis of this solution, a fibrous precipitate was re-formed. In contradistinction, the precipitates obtained from solutions of tendon in acetic acid at concentrations more generally used (0.01–0.4 per cent)2 are insoluble in 0.9 per cent sodium chloride. The physical properties of reconstituted collagen thus vary according to the concentration of the acetic acid used for dissolving the original tendon.
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References
v. Buzagh, A., Kolloidzschr., 101, 149 (1942).
Nageotte, J., C.R. Acad. Sci., Paris, 184, 115 (1927).
Jackson, D. S., Biochem. J., 54, 638 (1953).
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JACKSON, D., BALL, J. A Soluble Form of Reconstituted Collagen. Nature 172, 1046 (1953). https://doi.org/10.1038/1721046a0
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DOI: https://doi.org/10.1038/1721046a0
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