Abstract
AROMATIC C-nitration through attack by the nitronium ion was kinetically established by the work of Benford and Ingold1, and of Hughes, Ingold and Reed2. The central point in the evidence was the observation of zeroth-order kinetics in the nitration of suitably reactive aromatic compounds, for example, of toluene, by a constant excess of nitric acid, in organic solvents such as nitromethane or acetic acid. All those aromatic compounds which are sufficiently reactive to take up the nitronium ion as fast as it is formed from nitric acid obey this law, and, for the same medium and temperature, can be observed to become nitrated at an identical rate, which is simply the rate of formation of the nitronium ion.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
J. Chem. Soc., 929 (1938).
Nature, 158, 448 (1946); J. Chem. Soc., 2400 (1950).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BLACKALL, E., HUGHES, E. N-Nitration and C-Nitration by the Nitronium Ion. Nature 170, 972–973 (1952). https://doi.org/10.1038/170972b0
Issue Date:
DOI: https://doi.org/10.1038/170972b0
This article is cited by
-
Nitration of pentaerythritol by HNO3-H2SO4-H2O system
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science (1970)
-
Esterification by the Nitronium Ion in Aqueous Perchloric Acid
Nature (1957)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.