Abstract
Between 1990 and 1996, three patients (1.1%), all with CML, among 272 patients with haematological malignancies, developed bilateral subdural haematomas (SDH) after treatment with i.t. MTX before HSCT in our unit. Since October 1996, we have given i.t. MTX only to patients at increased risk of CNS leukaemia such as ALL and AML M4 or M5. We suggest that intrathecal treatment before HSCT should only be given to patients at increased risk of CNS leukaemia.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hentschke, P., Hägglund, H., Mattsson, J. et al. Bilateral subdural haematomas following lumbar puncture in three haematopoietic stem cell transplant recipients. Bone Marrow Transplant 24, 1033–1035 (1999). https://doi.org/10.1038/sj.bmt.1702018
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.bmt.1702018
Keywords
This article is cited by
-
Use of intrathecal chemoprophylaxis in children after SCT and the risk of central nervous system relapse
Bone Marrow Transplantation (2011)
-
Lumbar puncture and subdural hygroma and hematomas in hematopoietic cell transplant patients
Bone Marrow Transplantation (2008)
-
Use of intrathecal prophylaxis in allogeneic haematopoietic stem cell transplantation for malignant blood diseases: a survey of the European Group for Blood and Marrow Transplantation (EBMT)
Bone Marrow Transplantation (2005)
-
CT and MR imaging of central nervous system effects of therapy in patients treated for hematological malignancies
European Radiology (2003)
