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Acute skin GVHD following syngeneic BMT for CLL

Bone Marrow Transplantation volume 22, pages 1207–1209 (1998)Cite this article

Abstract

A 41-year-old woman received a syngeneic BMT for CLL and subsequently developed acute skin GVHD. Transfusion-related allogeneic GVHD was excluded on the basis of an unchanged HLA type in circulating lymphocytes. Short tandem repeat PCR was used to confirm syngeneicity between donor and recipient. The patient had a personal and family history of autoimmune disease which may have made her particularly susceptible to development of syngeneic GVHD. The distinction between allogeneic and syngeneic or autologous GVHD is important because of therapeutic implications.

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Author notes

  1. M Deane

    Present address: Haematology Department, Norfolk & Norwich Hospital, Norwich, UK

  2. K Gomez

    Present address: Haematology Department, West Middlesex Hospital, London, UK

Authors and Affiliations

  1. Haematology Department, Royal Free Hospital and School of Medicine, London, UK

    M Deane, K Gomez & HG Prentice

  2. Haematology Department, Royal United Hospital, Bath, UK

    C Singer

  3. Haematology Department, Sir Patrick Dun Trinity Research Laboratory, St James’s Hospital, Dublin, Ireland

    M Lawler & S McElwaine

Authors
  1. M Deane
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  2. C Singer
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  3. M Lawler
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  4. S McElwaine
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  5. K Gomez
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  6. HG Prentice
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Deane, M., Singer, C., Lawler, M. et al. Acute skin GVHD following syngeneic BMT for CLL. Bone Marrow Transplant 22, 1207–1209 (1998). https://doi.org/10.1038/sj.bmt.1701515

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  • DOI: https://doi.org/10.1038/sj.bmt.1701515

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