Abstract
We describe a 4-month-old child who developed unusual thrombotic complications following allogeneic BMT for Omenn syndrome, a form of SCID. Eight weeks after the procedure the child suffered a major cerebrovascular accident and developed acute pulmonary hypertension in association with persistently elevated anticardiolipin antibody titres. It is postulated that central line-derived microemboli caused these serious thrombotic complications in the context of an evolving hypercoaguable state.
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Qasim, W., Gerritsen, B. & Veys, P. Anticardiolipin antibodies and thromboembolism after BMT. Bone Marrow Transplant 21, 845–847 (1998). https://doi.org/10.1038/sj.bmt.1701184
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DOI: https://doi.org/10.1038/sj.bmt.1701184
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