Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Interference Microscopy and Mass Determination

Abstract

THE development of phase-contrast and interference-contrast methods has focused attention on the possibility of improved accuracy in the determination of refractive indices of microscopic objects, particularly living cells1. In many cases immersion methods can conveniently be used2, but with living cells no great variation in the refractive index of the immersion medium can be tolerated.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Dyson, J., Proc. Roy. Soc., A, 204, 170 (1950).

    Article  ADS  Google Scholar 

  2. Oettlé, A. G., J. Roy. Micr. Soc., 70, 232 (1950).

    Article  Google Scholar 

  3. Bauer, N., and Fajans, K., in Weissberger, A., “Physical Methods of Organic Chemistry”, 1, pt. 2, 1141 (Interscience, New York 1949).

    Google Scholar 

  4. Adair, G. S., and Robinson, M. E., Biochem. J., 24, 993 (1930).

    Article  CAS  Google Scholar 

  5. Craig, J., and Schmidt, C. L. A., Aust. J. Exp. Biol. and Med Sci., 9, 33 (1932).

    Article  CAS  Google Scholar 

  6. Adair, G. S., Ogston, A. G., and Johnston, J. P., Biochem. J., 40, 867 (1946).

    Article  CAS  Google Scholar 

  7. Whitby, L. E. H., and Britton, C. J. C., “Disorders of the Blood” (Churchill, London, 1950).

    Google Scholar 

  8. Barer, R., Proc. Internat. Colloquium on Phase-Contrast and Interference Contrast (Paris, 1951, in the press); Optica Acta (in the press).

  9. Cecil, R. (personal communication, 1951).

  10. Gulland, J. M., Jordan, D. O., and Threlfall, C. J., J. Chem. Soc., 1129 (1947).

  11. Tennent, H. G., and Vilbrandt, C. F., J. Amer. Chem. Soc., 65, 424 (1943).

    Article  CAS  Google Scholar 

  12. Engström, A., and Lindström, B., Biochim. et Biophys. Acta. 4, 351 (1950). Engström, A., Discuss. Farad. Soc., 9, 427 (1950).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

BARER, R. Interference Microscopy and Mass Determination. Nature 169, 366–367 (1952). https://doi.org/10.1038/169366b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/169366b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing