Abstract
I HAVE already shown1 that the diphtherial culture filtrate harvested from the chemically defined media (A.M.C. and A.M.T. medium) containing two (asparagine, DL-methionine) or three amino-acids (asparagine, DL-methionine and L-cystin) as a nitrogen source had a very low toxicity for guinea pigs, while it showed a high degree of flocculation units.
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References
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YONEDA, M. Low Toxicity of the Diphtherial Culture Filtrate and its Relation to the Absence of Tyrosine in the Medium. Nature 168, 879–880 (1951). https://doi.org/10.1038/168879a0
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DOI: https://doi.org/10.1038/168879a0
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