Abstract
THE natural history of mammalian hepatitides viruses supports the concept of a widespread unapparent infection1,2 which makes it extremely difficult to study the problem by experimental inoculations without a reliable serological test. This communication describes a simple method for the purification and concentration (if necessary) of the antigen, as well as the preparation of the active antiserum for serological studies. Four strains of the virus have been used in these experiments : two English strains, one from Australia and one from Sweden.
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References
Rivers, T. M., “Viral and Rickettsial Infections of Man” (J. B. lippincott Co., Philadelphia–London–Montreal, 1948).
Parry, H. B., Larin, N. M., and Platt, H., J. Hyg., Camb. (in the press).
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LARIN, N. Preparation of the Specific Purified Antigen of Canine Hepatitis Virus and Antiserum for Serological Studies. Nature 168, 745–746 (1951). https://doi.org/10.1038/168745b0
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DOI: https://doi.org/10.1038/168745b0
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