Abstract
Patton and Chism1 have recently used paper chromatography followed by examination of the unheated papers under an ultra-violet lamp for demonstrating a series of fluorescent products in boiled glucose–glycine solutions. We have been using a similar technique in an investigation of the reaction between glucose and α-N-acetyl-L-lysine at 37° C. and have found it particularly effective when combined with a study of the effect of water content on the course of the reaction.
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References
Patton, A. R., and Chism, P., Nature, 167, 406 (1951).
Maillard, L. C., C.R. Acad. Sci., Paris, 154, 66 (1912).
Gottschalk, A., and Partridge, S. M., Nature, 165, 684 (1950).
Lea, C. H., and Hannan, R. S., Biochim. Biophys. Acta, 3, 313 (1949).
Lea, C. H., and Hannan, R. S., Biochim. Biophys. Acta, 4, 518 (1950).
Hannan, R. S., Ph.D. thesis, University of Cambridge (1951).
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HANNAN, R., LEA, C. Reaction between Glucose and the Terminal Amino Group of Lysine. Nature 168, 744–745 (1951). https://doi.org/10.1038/168744b0
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DOI: https://doi.org/10.1038/168744b0
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