Fertilizing Capacity of Spermatozoa deposited into the Fallopian Tubes


IN the natural sequence of mammalian fertilization, the spermatozoa await the arrival of ova in the Fallopian tubes. The time of waiting may vary from 6 hr. (rabbit), 24 hr. (ferret), 20–30 hr. (pig, sheep and cattle) up to perhaps several months (bat)1. Since the transportation of sperm from the vagina to the upper part of the tube is very rapid (a few minutes to 6 hr.1), and since the number of spermatozoa present at the site of fertilization is very small1, this time interval is not necessarily for the accumulation of a large number of spermatozoa to ensure fertilization. The following experiment demonstrates that such a period of time in the female tract is required for the spermatozoa to acquire their fertilizing capacity.

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  1. 1

    cf. Chang, M. C., and Pincus, G., Physiol. Rev., 31, 1 (1951).

    CAS  Article  Google Scholar 

  2. 2

    Chang, M. C., Proc. U.S. Nat. Acad. Sci., 36, 188 (1950).

    ADS  CAS  Article  Google Scholar 

  3. 3

    Hammond, J., J. Exp. Biol., 11, 140 (1934).

    Google Scholar 

  4. 4

    Austin, C. R., J. Endocrinol., 6, 63 (1949).

    CAS  Article  Google Scholar 

  5. 5

    Runner, M., Anat. Rec., 99, 564 (1947).

    CAS  PubMed  Google Scholar 

  6. 6

    Lardy, H. A., Ghosh, D., and Plaut, G. W. E., Science, 109, 365 (1949).

    ADS  CAS  Article  Google Scholar 

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CHANG, M. Fertilizing Capacity of Spermatozoa deposited into the Fallopian Tubes. Nature 168, 697–698 (1951). https://doi.org/10.1038/168697b0

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