Abstract
IT has been shown by Adams and Whittaker1–4 that both forms of mammalian cholinesterase hydrolyse aliphatic esters, those of 3 : 3-dimethyl-butanol (I), the carbon analogue of choline (II), being particularly rapidly hydrolysed. Thus human2 and horse5 erythrocyte cholinesterase hydrolyse 3 : 3-dimethylbutyl acetate at 1.8 and 1.6 times the rate of acetyl-β-methylcholine respectively. It is therefore of interest to know something of the pharmacological properties of this compound. 
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References
Adams, D. H., and Whittaker, V. P., Biochem. J., 43, xiv (1948).
Adams, D. H., Biochim. et Biophys. Acta, 3, 1 (1949).
Adams, D. H., and Whittaker, V. P., Biochim. et Biophys. Acta, 3, 358 (1949).
Whittaker, V. P., Biochem. J., 44, xlvi (1949).
Mounter, L. A., and Whittaker, V. P., Biochem. j., 47, 525 (1950).
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BANISTER, J., WHITTAKER, V. Pharmacological Activity of the Carbon Analogue of Acetylcholine. Nature 167, 605–606 (1951). https://doi.org/10.1038/167605b0
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DOI: https://doi.org/10.1038/167605b0
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