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Milk Ejection following Electrical Stimulation of the Pituitary Stalk in Rabbits

Abstract

CONSIDERABLE indirect evidence exists1 for the involvement of the posterior pituitary gland in ‘let-down’ or ejection of milk. Experiments were performed to find the effect of electrical stimulation of the pituitary stalk on the mammary glands in six lactating rabbits. After overnight separation from their litters, the animals were anæsthetized with ether, and a single teat-duct was cannulated and connected to a kymographic volume-recording system. A glass-insulated platinum wire electrode with 1 mm. bare tip mounted on a stereotaxic instrument was used for stimulation. A standard stimulus of 1 min. duration was adopted with 1.0 volt, 50 cycles sine-wave alternating current.

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References

  1. Folley, S. J., and Malpress, F. H., “The Hormones1, 695–805 (New York: Academic Press, 1948).

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  2. Cross, B. A., [Nature, 166, 612 (1950)].

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CROSS, B., HARRIS, G. Milk Ejection following Electrical Stimulation of the Pituitary Stalk in Rabbits. Nature 166, 994–995 (1950). https://doi.org/10.1038/166994b0

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