New Techniques in Autoradiography

Abstract

THE recent communication of Winteringham¹ has focused attention on the two main difficulties which limit the value of the autoradiographic method in the study of the distribution of soluble radioisotopes of short half-life. These two problems, that of preparing the tissue without loss of the soluble tracer, and the enormous radiation intensities needed for a successful exposure, have been largely solved in our work; and in view of the general usefulness of the methods employed, a preliminary publication of their essential features may not be out of place.