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Concentration and Distribution of Polysaccharides in Human Cortical Bone and the Dentine of Teeth

Nature volume 164, pages 625–626 (1949)Cite this article

Abstract

THE probable presence of a sulphated polysaccharide in bone has been recognized for many years1. Recently, attention has been redirected to the subject by the isolation2 of a substance claimed to be identical with chondrontin sulphate, which is known to be one of the principal constituents of cartilage1,3, from dentine of human teeth. As a basis for future work on the organic matrix of bone and teeth it seems to be of importance to know: (1) the order of concentration of the mucopolysaccharides in them ; (2) the changes, if any, which take place with age ; (3) the distribution of polysaccharide. The present work is a contribution to problems (1) and (3). Insufficient samples have yet been analysed to give an answer to point (2), but the following is a preliminary summary of the results so far obtained.

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Authors and Affiliations

  1. Biological Research Unit, Dental School and Hospital, Blundell Street, Leeds, 1

    H. J. ROGERS

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  1. H. J. ROGERS
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ROGERS, H. Concentration and Distribution of Polysaccharides in Human Cortical Bone and the Dentine of Teeth. Nature 164, 625–626 (1949). https://doi.org/10.1038/164625a0

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