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Fractionation of Thyroid Iodine by means of Filter-Paper Partition Chromatography

Abstract

BY means of filter-paper partition chromatography, Fink, Dent and Fink1 located several different radioiodine fractions in hydrolysates prepared from thyroids of rats that had been injected 24–28 hours earlier with iodine-131. Surprisingly, little or none of the radioactivity was found as thyroxine. Since this is not in accord with previous results from this laboratory2, we examined the method of filter-paper chromatography as applied to thyroid iodine.

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References

  1. Fink, R. M., Dent, C. E., and Fink, K., Nature, 160, 801 (1947).

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  2. Chaikoff, I. L., and Taurog, A., “Symposium on the Use of Isotopes in Biology and Medicine", 292 (Univ. of Wisconsin Press, 1948).

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  3. Taurog, A., and Chaikoff, I. L., J. Biol. Chem., 169, 49 (1947).

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TAUROG, A., TONG, W. & CHAIKOFF, I. Fractionation of Thyroid Iodine by means of Filter-Paper Partition Chromatography. Nature 164, 181–182 (1949). https://doi.org/10.1038/164181b0

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