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Interference with Testosterone-induced Growth of the Seminal Vesicles and Coagulating Glands in Male Mice by a Folic Acid Antagonist

Nature volume 164, pages 62–63 (1949)Cite this article

Abstract

IT has been established that adequate amount, of folic acid are necessary for the elicitation by œstrogens of the growth response of the female genital tract in the chick1,2 and monkey3. Recently, it has been reported that folic acid antagonists markedly decreased the growth response to œ"strogens of the genital tracts of the female chick4,5, rodent6 and frog7.

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References

  1. Hertz, R., Endocrin., 37, 1 (1945).

    Article  CAS  Google Scholar 

  2. Kline, I. T., and Dorfman, R. I., J. Clin. Endocrin., 8, 602 (1948).

    CAS  Google Scholar 

  3. Hertz, R., Proc. Soc. Exp. Biol. and Med., 67, 113 (1948).

    Article  CAS  Google Scholar 

  4. Hertz, R., Science, 107, 300 (1948).

    Article  ADS  CAS  Google Scholar 

  5. Franklin, A. L., Lewis, D., Stokstad, E. L. R., and Jukes, T. H., 37th Annual Meeting, Poultry Science Association, Poultry Sci. 27, 662 (1948).

    Google Scholar 

  6. Hertz, R. (in the press, personal communication).

  7. Goldsmith, E. D., Schreiber, S. S., and Nigrelli, R. F., Proc. Soc. Exp. Biol. and Med., 69, 299 (1948).

    Article  CAS  Google Scholar 

  8. Bittner, J. J., “Biology of the Laboratory Mouse", 321 (edited by G. D. Snell, Blakiston, 1941).

    Google Scholar 

  9. Franklin, A. L., Stokstad, E. L. R., and Jukes, T. H., Proc. Soc. Exp. Biol. and Med., 65, 368 (1947).

    Article  CAS  Google Scholar 

  10. Huggins, C., Physiol. Rev., 25, 281 (1945).

    Article  CAS  Google Scholar 

  11. Huggins, C., Stevens, R. E., jun., and Hodges, C. V., Arch. Surg., 43, 209 (1941).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Histology, College of Dentistry, New York University,

    E. D. GOLDSMITH, HERMAN M. BLACK & Ross F. NIGRELLI

  2. New York Aquarium, New York Zoological Society,

    E. D. GOLDSMITH, HERMAN M. BLACK & Ross F. NIGRELLI

Authors
  1. E. D. GOLDSMITH
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  2. HERMAN M. BLACK
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  3. Ross F. NIGRELLI
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GOLDSMITH, E., BLACK, H. & NIGRELLI, R. Interference with Testosterone-induced Growth of the Seminal Vesicles and Coagulating Glands in Male Mice by a Folic Acid Antagonist. Nature 164, 62–63 (1949). https://doi.org/10.1038/164062b0

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