Trypsin splitting and denaturation of β-Lactoglobulin


LINDERSTRØM-LANG, Hotchkiss and Johansen 1 have stressed the importance of denaturation in the proteolytic splitting of globular proteins. They suppose that the process genuine denatured is forced in tjae direction of the right-hand side of the equation by splitting of the D-form, both forms gradually disappearing ; and they suggest that the pepfcme bonds as such are masked in native globular proteins, and first 'appear' on denaturation.


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Christensen, L. Trypsin splitting and denaturation of β-Lactoglobulin. Nature 163, 1003–1004 (1949).

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