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Increased Muscle Phosphorylase Activity in the Starved Rat

Abstract

IT was shown earlier that glucose uptake in the isolated rat diaphragm was reduced after a period of non-carbohydrate, high-fat diet1, and that a spontaneous regulation of food intake took place in animals shifted from such a diet to a high-carbohydrate diet2. These physiological changes occurring after a period of carbohydrate deprivation, together with many other observations after starvation or fat-feeding by other investigators, suggest that the kind of foodstuff taken by the animal (or human subject) determines in some way the metabolic pattern.

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LUNDBÆK, K., GORANSON, E. Increased Muscle Phosphorylase Activity in the Starved Rat. Nature 162, 1002–1003 (1948). https://doi.org/10.1038/1621002b0

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