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A Vasodilator, Adrenolytic Substance in Aglomerular Fish Kidney

Abstract

EXPERIMENTS were performed on aglomerular fish kidneys to establish the presence or absence of vaso-active substances. This communication deals with the presence of an adrenolytic, vasodilator substance in extracts of the aglomerular kidneys of the toadfish (Opsanus tau). The material extracted was tested for its vasodilator properties on the peripheral blood vessels and capillaries of the frog (Rana pipiens), and also for its adrenolytic ability, that is, ability to neutralize and protect against the vasoconstrictor effect of epimephrine.

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References

  • Jablons, B., Trans. Amer. Physiol. Soc. (1935).

  • Jablons, B., N.Y. State J. Med., 38, No. 1 (1938).

  • Cope, Otis M., and Jablons, B., Fed. Proc., 2, 90 (1947).

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JABLONS, B. A Vasodilator, Adrenolytic Substance in Aglomerular Fish Kidney. Nature 161, 100–101 (1948). https://doi.org/10.1038/161100b0

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