Abstract
Jeffers, Lindauer, Twaddle and Wolferth1 reported in 1940 that removal of three of the four kidneys in a pair of parabiotic rats resulted in hypertension in the nephrectomized animal. Grollman and Rule2 found in two pairs of parabiotic rats that removal of the kidneys in one animal sufficed to induce hypertension. When these experiments were repeated by one of us (E. B.-M.) a definite rise in blood pressure was found only in three out of twenty-three pairs, however.
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Jeffers, W. A., Lindauer, M. A., Twaddle, P. H., and Wolferth, C. C., Amer. J. Med. Sci., 199, 815 (1940).
Grollman, A., and Rule, C., Amer. J. Physiol., 138, 587 (1942).
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BRAUN-MENÉNDEZ, E., V. EULER, U. Hypertension after Bilateral Nephrectomy in the Rat. Nature 160, 905 (1947). https://doi.org/10.1038/160905a0
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DOI: https://doi.org/10.1038/160905a0
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