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Hydrochloric Acid Formation in the Gastric Mucosa

Abstract

IN a recent article1 concerning the mechanism of high acid production by bakers' yeast and its bearing on hydrochloric acid formation in the stomach, reference was made by us to the work of Davies et al.2,3 on the respiratory exchange and hydrochloric acid production by the gastric mucosa of the frog. It was pointed out that though such results appear of value for the theory of formation of hydrochloric acid, they in no way disprove the essentials of the theory proposed from our Department as to the manner of formation of the acid4. After reading the recent communication of Davies et al.5, we can only reaffirm our conclusions in this respect concerning their data.

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References

  1. Conway, E. J., and Brady, T. G., Nature, 159, 137 (1947).

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  2. Davies, R. E., Biochem. J., 40, Proc. xxxv (1946).

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  3. Davies, R. E., and Longmuir, N. M., Biochem. J., 40, Proc. lxiv (1946).

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  4. Conway, E. J., FitzGerald, O., and Walls, D., Nature, 156, 477 (1945).

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  5. Davies, R. E., Longmuir, N. M., and Crane, E. E., Nature, 159, 468 (1947).

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  8. Davies R. E., Longmuir, N. M., and Crane, E. E., Biochem. J., 40, Proc. xxxvi (1946).

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CONWAY, E., BRADY, T. Hydrochloric Acid Formation in the Gastric Mucosa. Nature 159, 876–877 (1947). https://doi.org/10.1038/159876a0

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