Abstract
FOR a number of years our laboratories have been conducting investigations on natural cellular substances, some of which are stimulatory and some inhibitory to growth of tissues and microorganisms1,2,3,4. In connexion with the work on bacteria, we recently reported a substance isolated from both human and ox spleens which, in vitro, was germicidal in concentration as low as 1 part in 2,000 for Streptococcus hœmolyticus5. The present investigations, conducted on Staphylococcus aureus, were undertaken as an extension of this work with spleen extract and also include observations on various other ox tissue extracts, primarily brain, heart and kidney.
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References
Sperti, Loofbourow and Dwyer, Studies Inst. Divi Thomae, 1, 163 (1937).
Fardon and Sullivan, Studies Inst. Divi Thomae, 2, 39 (1938–39).
Cook, Kreke Giersch and Schroeder, Science, 93, 616 (1941).
Schroeder and Hollencamp, Studies Inst. Divi Thomae, 3, 193 (1941).
Nutini and Kreke, J. Bact., 44, 661 (1942).
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NUTINI, L., LYNCH, E. Effect of Tissue Extracts in controlling Staphylococcus aureus Infections. Nature 156, 419–420 (1945). https://doi.org/10.1038/156419a0
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DOI: https://doi.org/10.1038/156419a0
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