Abstract
AN antibody of a type hitherto undescribed, which discriminates between certain Rhesus genotypes, has been found in the serum of a male patient, H.Br., of blood group O, suffering from a hæmolytic anæmia of uncertain ætiology. He was transfused on numerous occasions with unselected group O blood and ultimately began to have reactions suggestive of incompatibility. His serum was found to contain an agglutinin which clumped the red cells of all but about 4 per cent of group O donors. The cells of one group O Rhesus-negative subject, C.K., were agglutinated down to a dilution of 1 in 640 by serum obtained in April 1944. In May 1944 the titre against cells of the same subject had fallen to 80 and in January 1945 to 20. Most of the investigation was carried out with the May serum.
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References
See Race, Nature, 153, 771 (1944).
Race and Taylor, Nature, 152, 300 (1943).
Race, Taylor, Boorman and Dodd, Nature, 152, 563 (1943).
Murray, Race and Taylor, Nature, 155, 112 (1945).
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MOURANT, A. A New Rhesus Antibody. Nature 155, 542 (1945). https://doi.org/10.1038/155542a0
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DOI: https://doi.org/10.1038/155542a0
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