Letter | Published:

Wharton's Jelly Considered as a Conducting Path

Nature volume 154, page 667 (25 November 1944) | Download Citation



DURING the course of experiments conducted on the sheep foetus, dyes were injected into the umbilical cord with the object of exploring movements of substances in the cord along non-vascular pathways. The dyes used were a dis-azo dye, related to trypan blue, and the same dye linked to serum albumin by a diazo linkage. The dye, when linked to protein in this way, cannot dissociate from the albumin, and hence acts as a tag to the protein. These substances were prepared by one of us (P.D.M.).


  1. 1.

    , Proc. Roy. Soc., 24, 417 (1875).

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  1. Unit of Animal Physiology (Agricultural Research Council), Departments of Biochemistry and Zoology, Cambridge, and the Department of Anatomy, London Hospital Medical College.

    • , J. F. DANIELLI
    • , W. F. HARPER
    •  & P. D. MITCHELL


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