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p-Cresol and Œstrone in Urine
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  • Published: 17 June 1944

p-Cresol and Œstrone in Urine

  • N. R. CAMPBELL1 &
  • D. H. HEY1 

Nature volume 153, page 745 (1944)Cite this article

  • 221 Accesses

  • 4 Citations

  • Metrics details

Abstract

THE presence of p-cresol in human urine, as well as in the urine of horses, cows and other animals, has been known for a long time. It occurs mainly as a salt of p-tolylsulphuric acid. According to Siegfried and Zimmermann1, the average concentration of p-cresol in normal human urine is of the order of 18 mgm. per litre, and in a man with an, adrenal tumour a value of 25 mgm. per litre has been reported2. In the urine of pregnant mares, Marshall has found that the concentration is 60 mgm. per litre3.

References

  1. Siegfried and Zimmermann, Biochem. Z., 34, 471 (1911).

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  2. Burrows, Cook, Roe and Warren, Biochem. J., 31, 950 (1937).

    Article  CAS  Google Scholar 

  3. Marshall, NATURE, 140, 362 (1937).

  4. Zondek, NATURE, 133, 209 (1934).

  5. Falsia, C.R. Soc. Biol., 111, 395 (1932).

    CAS  Google Scholar 

  6. Fricke, Pflügers Archiv., 156, 225 (1914).

    Article  CAS  Google Scholar 

  7. Dodds, Helv. Chim. Acta, 19, E 49 (1936).

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. British Schering Research Institute, Alderley Edge, Cheshire

    N. R. CAMPBELL & D. H. HEY

Authors
  1. N. R. CAMPBELL
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  2. D. H. HEY
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CAMPBELL, N., HEY, D. p-Cresol and Œstrone in Urine. Nature 153, 745 (1944). https://doi.org/10.1038/153745a0

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  • Issue Date: 17 June 1944

  • DOI: https://doi.org/10.1038/153745a0

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This article is cited by

  • Identification of p-Cresol as a Toxin in Œstrogen Concentrates from Sheep Urine

    • E. P. WHITE
    • O. K. SEWELL
    • E. G. BASSETT

    Nature (1950)

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