Letter | Published:

Enamel Organ of the Rat's Incisor Tooth in Vitamin E Deficiency

Nature volume 150, pages 122123 (25 July 1942) | Download Citation



Davies and Moore1 have pointed out that rats on a diet deficient in vitamins A and E suffered from a secondary vitamin A deficiency as evidenced by a disappearance of the vitamin from the liver ; and also by a whitening of the incisor teeth, an effect which occurs in prolonged vitamin A deficiency2 and was prevented by vitamin E dosage. Through the kindness of Dr. H. E. Brink, Department of Physiology, University of Stellenbosch, who has been working on vitamin E deficiency, I have been able to examine the incisor teeth of three female rats which had been on a vitamin E deficient diet3 for 167 days from weaning. They had shown complete resorption of ambryos and the characteristic paralysis of the hind legs had just set in. The incisor teeth had the normal orange colour.

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  1. 1.

    , and , NATURE, 148, 794 (1941).

  2. 2.

    , and , Amer. J. Path., 9, 275 (1933); , and , J. Home Econ., 25, 411 (1933); , and , NATURE, 144, 908 (1939).

  3. 3.

    , Arch. néer. Physiol., 19, 403 (1934).

  4. 4.

    , , and , Amer. J. Path., 17, 529 (1941).

  5. 5.

    , Thesis, Univ. of Illinois. Quoted from ref. 4.

  6. 6.

    , and , unpublished results.

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  1. Department of Physiology, University of Cape Town.

    • J. T. IRVING


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