Abstract
EQUATIONS describing potassium equilibria across cells have been considered in a previous communication1, and more fully elsewhere2, with experimental proof of the principles involved with respect to potassium accumulation. Such potassium equilibria are largely conditioned by the nature of the products formed in the cell, especially the phosphate esters, and by the characteristic permeabilities of the membrane. That there is some association of potassium with phosphate is evident if only from an inspection of ash analyses, but the real problem for this special cation accumulation has lain in the manner of its occurrence and physiological significance. With this latter, or functional value, as distinct from mechanism the present communication is concerned.
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References
Conway, E. J., NATURE, 144, 709 (1939).
Boyle, P. J., and Conway, E. J., J. Physiol. (in the press, 1941).
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CONWAY, E. Physiological Origins of Cellular Potassium. Nature 147, 574–575 (1941). https://doi.org/10.1038/147574a0
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DOI: https://doi.org/10.1038/147574a0
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