Abstract
KNOWLEDGE of the detailed action of vitamin B1 in Nature has advanced farther than in the case of any other vitamins with the possible exception of riboflavin, and nicotinic acid; even in the case of these, detailed knowledge has come to hand more recently. This is not only due to the striking advances in the pure chemistry but also to the fortunate circumstance that it was the first vitamin in which specific action in vitro upon an animal tissue was demonstrated1. Since its action is so intimately bound up with a fundamental stage in the degradation of carbohydrate, it justifies in a way the conception originally lying behind the use of the word ‘vitamine’ by Funk. Useful as the new terms for this vitamin ‘aneurin’ and ‘thiamin’ undoubtedly are, it seems a pity to lose sight of the idea of the “amine essential for life”, because in a way this is very nearly true. Formation of carbon dioxide depends more upon this factor than upon any other.
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PETERS, R. Cocarboxylase. Nature 146, 387–391 (1940). https://doi.org/10.1038/146387a0
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DOI: https://doi.org/10.1038/146387a0
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