Abstract
IT is true, as Miss Melland states, that the nucleolus as it grows can interfere mechanically with the structure of a chromosome. It can, for example, stretch the filament which connects the satellite with the body of the chromosome. This is done by de-spiralizing the filament. Nevertheless the filament appears to be a spiral of a lower order than the spiral chromonemata which make up the body of the chromosome. It is already present in anaphase chromosomes before the nucleolus begins to appear the same is true of secondary constrictions which give rise to nueleoli. These features of chromosome structure are for this and other reasons not produced by the growing nucleolus merely pushing the gyres of the spiral chromonema apart.
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GATES, R. Relation of the Nucleolus to Secondary Constrictions. Nature 144, 980 (1939). https://doi.org/10.1038/144980c0
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DOI: https://doi.org/10.1038/144980c0
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