Abstract
FOR a long time it has been known that heating under various degrees of the ester of glycine1, glycyl-glycine2 and diglycyl-glycine3 results in the formation of certain condensation products with liberation of alcohol. If the hexapeptide ester of glycine would undergo the type of condensation exhibited by the dipeptide ester, then the simplest model of a ‘cyclol 6’ postulated by the Wrinch theory4 could be prepared. The formation of such ‘cyclo-hoxapeptide’ of glycine could then be considered as evidence for the hexagonal folding by hydrogen bonds of the polypeptide chains.
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References
Curtius, Th., Ber., 37, 1289 (1904).
Fischer, E., and Fourneau, E., Ber., 34, 2868 (1901).
Fischer, E., Ber., 39, 453 (1906).
Wrinch, D. M., NATURE, 137, 411 (1936), et seq.; Proc. Roy. Soc., A, 160, 59 (1937).
Fischer, E., Ber., 39, 2893 (1906).
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PACSU, E. Condensation of the Hexapeptide Ester of Glycine into the 96- and Higher (3 × 2n) Peptide Esters. Nature 144, 551 (1939). https://doi.org/10.1038/144551a0
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DOI: https://doi.org/10.1038/144551a0
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