Abstract
TWO or three years ago some of us1, in common with other investigators2, recognized that the rat required at least four factors of the vitamin B complex—aneurin, riboflavin and two materials, then unidentified, which we named yeast eluate factor and yeast filtrate factor respectively. The yeast eluate factor has since been isolated and identified3 with vitamin B6. We have prepared from extracts of liver a fraction replacing the yeast filtrate factor in the diet of the rat4; this fraction we believe to contain a single factor, which we have named the liver filtrate factor. We have been for some time engaged on experiments having as their object the purification and eventual isolation of this factor.
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EL-SADR, M., HIND, H., MACRAE, T. et al. Vitamin B Requirements of the Rat. Nature 144, 73–74 (1939). https://doi.org/10.1038/144073a0
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DOI: https://doi.org/10.1038/144073a0
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