Abstract
WE have used the name ‘diaphorase’ to designate the enzyme which catalyses the transport of hydrogen from dihydrocodehydrogenase I (CoH2I) to acceptors like methylene blue or cytochrome, but not to molecular oxygen1,2,3. This enzyme, which had been detected independently by Dewan and Green4 (“coenzyme factor”), occurs in all animal tissues so far examined as well as in yeast5,6 and in higher plants7. Diaphorase from heart muscle, purified to some extent by precipitating a phosphate extract from washed tissues with low concentrations of acetone and ammonium sulphate2, was shown to attack CoH2 I specifically, that is, it was inactive against dihydrocodehydrogenase II (CoH2 II).
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Adler, Euler and Hellström, Sv. Vet. Ark. Kemi, 12 B, Nr. 38 (1937).
Euler and Hellström, Z. physiol. Chem., 252, 31 (1938).
Adler, Euler and Günther, Sv. Vet. Ark. Kemi, 12 B, Nr. 54 (1938).
Dewan and Green, NATURE, 140, 1097 (1937). Biochem, J., 32, 628 (1938).
Green and Dewan, Biochem. J., 32, 1200 (1938).
Euler and Günther, Naturwiss., 26, 676 (1938).
Lockhart, Biochem. J. (in the Press).
Adler, Euler, Günther and Plass, Skand. Arch. Physiol. (in the Press).
Euler and Adler, Svensk kem. tidskr., 51, 11 (1939).
Corran, Straub and Green, NATURE, 143, 337 (1939).
Warburg and Christian, Biochem. Z., 298, 368 (1938).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ADLER, E., v. EULER, H. & GÜNTHER, G. Diaphorase I and II. Nature 143, 641–642 (1939). https://doi.org/10.1038/143641b0
Issue Date:
DOI: https://doi.org/10.1038/143641b0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.